‘ANDA PENGGUNA BIJAK’
The Eurycoma Longifolia Freeze-Dried Water Extract-Physta Does not Change Normal Ratios of Testosterone to Epitestosterone in Healthy Males
1Biotropics Malaysia Berhad, Lot 21, Jalan U1/19, Section U1, Hicom-Glenmarie Industrial Park, 40150 Shah Alam, Selangor, MalaysiaGeorge A1*, 2Departments of Life Sciences, Technical University of Braunschweig, GermanyLiske E2, 3Sports Science Unit, School of Medical Sciences, Universiti Sains Malaysia, MalaysiaChen CK3 and 4Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, MalaysiaIsmail SB4
Biotropics Malaysia Berhad, Lot 21, Jalan U1/19
Section U1, Hicom-Glenmarie Industrial Park
40150 Shah Alam, Selangor, MalaysiaTel: 603-55655600Fax: 603-55655603E-mail: firstname.lastname@example.org
Received August 19, 2013; Accepted September 19, 2013; Published September 26, 2013
Citation: George A, Liske E, Chen CK, Ismail SB (2013) The Eurycoma Longifolia Freeze-Dried Water Extract-Physta® Does not Change Normal Ratios of Testosterone to Epitestosterone in Healthy Males. J Sports Med Doping Stud 3:127. doi: 10.4172/2161-0673.1000127
Copyright: © 2013 George A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Eurycoma longifolia is traditionally known for its adaptogenic properties and often used for the general well-being and increased performance in daily life.
Methods: In a randomized, double blind, placebo-controlled clinical trial, 40 Malaysian men aged 30-55 years performed a battery of physical testings during which the ratio of Testosterone (T) to Epitestosterone (E) was analyzed. The daily intake was 300 mg of the freeze-dried water extract of Eurycoma longifolia root (Physta®, Biotropics Malaysia) or placebo for a period of 12 weeks.
Results: At the end of the study the T/E-ratio in the herbal group ranged from 0.03 to 2.95 and was not significantly different from values at baseline (p=0.49). Further, the ratio-values for E. longifolia compared to placebo did not change over time. The weight lifting force which measures muscular strength using back & leg strength test, increased significantly from baseline to end of the study in the herbal group by approximately 14 kg (p=0.0166).
Conclusion: The ratios of testosterone to epitestosterone did not change during a 12-weeks E. longifolia intake. The data suggest that this herb does not exhibit “doping”- like effects. Instead, muscular strength improved significantly in the back and leg with E. longifolia supplementation rendering this herb good for physical performance minus the doping effects.